G Antibody, HRP conjugated

^{Rare Species}

Datasheet

Code	CSB-PA14899B0Rb
Size	US$166
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Target Background

Product Details

Full Product Name

Rabbit anti-Rabies virus G Polyclonal antibody

Uniprot No.

P03524

Target Names

Alternative Names

GGlycoprotein antibody

Raised in

Rabbit

Species Reactivity

Rabies virus

Immunogen

Recombinant Rabies virus Glycoprotein protein (20-459AA)

Immunogen Species

Rabies virus

Conjugate

HRP

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Description

G polyclonal antibody, HRP conjugated CSB-PA14899B0Rb was produced in the rabbit immunized by using the Recombinant Rabies virus Glycoprotein protein (20-459AA) as the immunogen. The target protein G can attach the virus to host cellular receptor, inducing endocytosis of the virion. In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between virus and cell membrane. There is convincing evidence that the muscular form of the nicotinic acetylcholine receptor (nAChR), the neuronal cell adhesion molecule (NCAM), and the p75 neurotrophin receptor (p75NTR) bind glycoprotein and thereby facilitate rabies virus entry into cells.
This Rabbit anti-Rabies virus G Polyclonal antibody was tested in the ELISA. The HRP-conjugated IgG got purified by protein G and reached up to 95% in purity. It only reacts with the G proteins of Rabies virus-origin and may be used to detect the endogenous levels of G protein.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function

Attaches the virus to host cellular receptor, inducing endocytosis of the virion. In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between virus and cell membrane. There is convincing in vitro evidence that the muscular form of the nicotinic acetylcholine receptor (nAChR), the neuronal cell adhesion molecule (NCAM), and the p75 neurotrophin receptor (p75NTR) bind glycoprotein and thereby facilitate rabies virus entry into cells.

Subcellular Location

Virion membrane; Single-pass type I membrane protein.

Protein Families

Lyssavirus glycoprotein family

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